VPS18 Antibody, Biotin conjugated | CSB-PA882173LD01HU

VPS18 Antibody, Biotin conjugated | CSB-PA882173LD01HU | Cusabio

VPS18 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: VPS18

Aliases: Vacuolar protein sorting-associated protein 18 homolog (hVPS18), VPS18, KIAA1475

Background: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25783203) . Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203) . Involved in dendrite development of Pukinje cells (By similarity) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q9P253

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 18 homolog protein (298-515AA)

Immunogen Species: Homo sapiens (Human)

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction