UVSSA Antibody, Biotin conjugated | CSB-PA012267LD01HU

UVSSA Antibody, Biotin conjugated | CSB-PA012267LD01HU | Cusabio

UVSSA Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: UVSSA

Aliases: UV-stimulated scaffold protein A, UVSSA, KIAA1530

Background: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q2YD98

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

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