UACA Antibody | CSB-PA025409ESR2HU

UACA Antibody | CSB-PA025409ESR2HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: UACA

Aliases: Uveal autoantigen with coiled-coil domains and ankyrin repeats, UACA, KIAA1561

Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9BZF9

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (1-90AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

Dilution Ratio3:

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Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology;Immunology