Txnip Antibody, Biotin conjugated | CSB-PA803849LD01MO

Txnip Antibody, Biotin conjugated | CSB-PA803849LD01MO | Cusabio

Txnip Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: Txnip

Aliases: Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1), Txnip, Vdup1

Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) . Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q8BG60

Host Species: Rabbit

Species Reactivity: Mouse

Immunogen: Recombinant Mouse Thioredoxin-interacting protein (1-397AA)

Immunogen Species: Mouse

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cell biology;Metabolism;Signal transduction