TTI1 Antibody, Biotin conjugated | CSB-PA012188LD01HU

TTI1 Antibody, Biotin conjugated | CSB-PA012188LD01HU | Cusabio

TTI1 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: TTI1

Aliases: TELO2-interacting protein 1 homolog (Protein SMG10), TTI1, KIAA0406 SMG10

Background: Regulator of the DNA damage response (DDR) . Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) . Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: O43156

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human TELO2-interacting protein 1 homolog protein (692-858AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics & Nuclear Signaling;Cell biology