TP53BP2 Antibody | CSB-PA622676ESR2HU

TP53BP2 Antibody | CSB-PA622676ESR2HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: TP53BP2

Aliases: Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2), TP53BP2, ASPP2 BBP

Background: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q13625

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Apoptosis-stimulating of p53 protein 2 protein (360-600AA)

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB; Recommended dilution: WB:1:200-1:1000

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:200-1:1000

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Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology