Cusabio Polyclonal Antibodies
TNFSF13B Antibody, Biotin conjugated | CSB-PA05767D0Rb
- SKU:
- CSB-PA05767D0Rb
- Availability:
- 3 to 7 Working Days
Description
TNFSF13B Antibody, Biotin conjugated | CSB-PA05767D0Rb | Cusabio
TNFSF13B Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: TNFSF13B
Aliases: Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form], TNFSF13B, BAFF BLYS TALL1 TNFSF20 ZTNF4
Background: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Isoform 3:Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly regulate the differential expression of a large number of genes involved in the innate immune response and the regulation of apoptosis.
Isotype: IgG
Conjugate: Biotin
Clonality: Polyclonal
Uniport ID: Q9Y275
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (68-285AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Cancer;Cell biology;Immunology