Timp1 Antibody | CSB-PA16719A0Rb

Timp1 Antibody | CSB-PA16719A0Rb | Cusabio

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Product Type: Polyclonal Antibody

Target Names: Timp1

Aliases: Metalloproteinase inhibitor 1 (Tissue inhibitor of metalloproteinases 1) (TIMP-1), Timp1, Timp-1

Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P30120

Host Species: Rabbit

Species Reactivity: Rat

Immunogen: Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA)

Immunogen Species: Rat

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Cancer;Cardiovascular;Cell biology;Signal transduction