SNX27 Antibody, HRP conjugated | CSB-PA842704LB01HU

SNX27 Antibody, HRP conjugated | CSB-PA842704LB01HU | Cusabio

SNX27 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SNX27

Aliases: Sorting nexin-27, SNX27, KIAA0488

Background: Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns (3P) ) . May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q96L92

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Sorting nexin-27 protein (458-497AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction