SMYD2 Antibody, Biotin conjugated | CSB-PA885705LD01HU

SMYD2 Antibody, Biotin conjugated | CSB-PA885705LD01HU | Cusabio

SMYD2 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SMYD2

Aliases: N-lysine methyltransferase SMYD2 (EC 2.1.1.-) (HSKM-B) (Histone methyltransferase SMYD2) (EC 2.1.1.43) (Lysine N-methyltransferase 3C) (SET and MYND domain-containing protein 2), SMYD2, KMT3C

Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2) . Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q9NRG4

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human N-lysine methyltransferase SMYD2 protein (115-272AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling