SLC5A8 Antibody, HRP conjugated | CSB-PA836676LB01HU

SLC5A8 Antibody, HRP conjugated | CSB-PA836676LB01HU | Cusabio

SLC5A8 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SLC5A8

Aliases: Sodium-coupled monocarboxylate transporter 1 (Apical iodide transporter) (Electrogenic sodium monocarboxylate cotransporter) (Sodium iodide-related cotransporter) (Solute carrier family 5 member 8), SLC5A8, AIT SMCT SMCT1

Background: Acts as an electrogenic sodium (Na (+) ) and chloride (Cl-) -dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na (+) :substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na (+) gradient and hence contribute to the maintenance of the energy status and function of neurons.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q8N695

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Sodium-coupled monocarboxylate transporter 1 protein (540-610AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Neuroscience;Cancer;Cell biology;Metabolism;Signal transduction