SLC38A9 Antibody, FITC conjugated | CSB-PA836713LC01HU

SLC38A9 Antibody, FITC conjugated | CSB-PA836713LC01HU | Cusabio

SLC38A9 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SLC38A9

Aliases: Sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9) (Up-regulated in lung cancer 11), SLC38A9, URLC11

Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906) . Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906) . The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906) .

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q8NBW4

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Metabolism;Signal transduction