scn Antibody | CSB-PA858805HA01SKY

scn Antibody | CSB-PA858805HA01SKY | Cusabio

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Product Type: Polyclonal Antibody

Target Names: scn

Aliases: Staphylococcal complement inhibitor (SCIN), scn

Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q99SU9

Host Species: Rabbit

Species Reactivity: Staphylococcus aureus

Immunogen: Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)

Immunogen Species: Staphylococcus aureus

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others