S100B Monoclonal Antibody | CSB-MA106771A0m

S100B Monoclonal Antibody | CSB-MA106771A0m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: S100B

Aliases: S100B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B

Relevance: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Isotype: IgG1

Conjugate: Non-conjugated

Clone Number: 1A1B1

Uniport ID: P04271

Alternatives To SCBT: sc-81709/sc-52206/sc-136061

Host Species: Mouse

Species Reactivity: Human

Immunogen: Recombinant Human S100B protein

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics and Nuclear Signaling;Cell biology;Stem cells