Cusabio Polyclonal Antibodies
RRAGA Antibody | CSB-PA03465A0Rb
- SKU:
- CSB-PA03465A0Rb
- Availability:
- 3 to 7 Working Days
Description
RRAGA Antibody | CSB-PA03465A0Rb | Cusabio
RRAGA Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: RRAGA
Aliases: Ras-related GTP-binding protein A (Rag A) (RagA) (Adenovirus E3 14.7 kDa-interacting protein 1) (FIP-1), RRAGA
Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q7L523
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)
Immunogen Species: Human
Applications: ELISA, IHC, IF
Tested Applications: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: IHC:1:20-1:200
Dilution Ratio3: IF:1:50-1:200
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Microbiology
Research Areas: Epigenetics & Nuclear Signaling;Cancer;Metabolism;Microbiology;Signal transduction