RHOB Antibody, Biotin conjugated | CSB-PA019683LD01HU

RHOB Antibody, Biotin conjugated | CSB-PA019683LD01HU | Cusabio

RHOB Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: RHOB

Aliases: Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6), RHOB, ARH6 ARHB

Background: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: P62745

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Rho-related GTP-binding protein RhoB protein (1-196AA)

Immunogen Species: Homo sapiens (Human)

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction