RELN Antibody | CSB-PA019557LA01HU

RELN Antibody | CSB-PA019557LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: RELN

Aliases: Reelin (EC 3.4.21.-), RELN

Background: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P78509

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Reelin protein (26-254AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:500

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:500

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience