Recombinant Orientia tsutsugamushi 56 KDA type-specific antigen | CSB-CF327749OCJ

Recombinant Orientia tsutsugamushi 56 KDA type-specific antigen | CSB-CF327749OCJ | Cusabio

Alternative Name(s): 56 KDA scrub typhus antigen STA56 TSS56

Gene Names: N/A

Research Areas: Others

Organism: Orientia tsutsugamushi(Rickettsia tsutsugamushi)

AA Sequence: IEFDENSLECGPYAKVGIVGGVLSGVESARLDPADSEGKKHLPLIKGMPFGVTLAAGMTITPGVRAEISAMYLMNVKAEVELGKMGSDANTGTTADASAGVIRKHKKLTPPQPNIMPISIADRDIAVDIPNAAGQGNVDVRAAARIAWLKNYAGIDYYVPDSNNPQGRVVNPVLLNIPQGNPNPAGGGGRAAPAAFDILDHAQWRDVVVGITALSNANKPNVSAVKILSDKISQIYADIKPFANVASVQISETPLPDSASVDQIQNKVQELNKVLEDVRESFDGFILNAFAQPVRLNFQIPQVVQGQGQQPQAAATAQEAAAAAAIRALNDGENNGIIQLYKDLYKLQRNVALKKSMKQLGDELGVDQGQEGGCSKDKKQSDTTAEESKKEGKKGKEIEFDLHMAVGQVKLYADLFTIDSFSVYAGIGAGLAYTHGKIDGKDIKAHTGMVGSLALGVAANVADGVYMDVDAGYLYSFSKIEEKYQMNAFVASAGIRYNF

Source: in vitro E.coli expression system

Tag Info: N-terminal 6xHis-tagged

Expression Region: 23-521aa

Sequence Info: Full Length of Mature Protein

MW: 57 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: May be an adherent factor for rickettsial adsorption to the host-cell surface and a determinant of virulence of individual rickettsial strain. It is the major outer membrane protein

Reference: "Diversity of immunodominant 56-KDA type-specific antigen (TSA) of Rickettsia tsutsugamushi. Sequence and comparative analyses of the genes encoding TSA homologues from four antigenic variants."Ohashi N., Nashimoto H., Ikeda H., Tamura A.J. Biol. Chem. 267:12728-12735(1992)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: May be an adherent factor for rickettsial adsorption to the host-cell surface and a determinant of virulence of individual rickettsial strain. It is the major outer membrane protein.

Involvement in disease:

Subcellular Location: Cell membrane, Multi-pass membrane protein

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P37917

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A