Recombinant Mouse Eotaxin protein (Ccl11) (Active) | CSB-AP001291MO

Recombinant Mouse Eotaxin protein (Ccl11) (Active) | CSB-AP001291MO | Cusabio

Protein Description: Full Length of Mature Protein

Alternative Name (s) : C-C motif chemokine 11, Small-inducible cytokine A11

Gene Names: Ccl11,Scya11

Research Areas: Immunology

Species: Mus musculus (Mouse)

Source: E.Coli

Tag Info: Tag-Free

Expression Region: 24-97aa

Sequence Info: HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000 ng/ml.

MW: 8.4 kDa

Purity: >96% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions) , but not lymphocytes, macrophages or neutrophils.

PubMed ID: 7568052; 8574847; 10438970; 16141072; 15489334; 9169149

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions) , but not lymphocytes, macrophages or neutrophils.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: Intercrine beta (chemokine CC) family

Tissue Specificity: Expressed constitutively in the thymus. Expression inducible in the lung (type I alveolar epithelial cells) , intestine, heart, spleen, kidney.

Paythway:

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P48298

Uniprot Entry Name: CCL11_MOUSE

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A