Cusabio Active Proteins
Recombinant Human Trefoil factor 2 protein (TFF2) (Active) | CSB-AP000351HU
- SKU:
- CSB-AP000351HU
- Availability:
- 5 to 10 Working Days
Description
Recombinant Human Trefoil factor 2 protein (TFF2) (Active) | CSB-AP000351HU | Cusabio
Protein Description: Full Length of Mature Protein
Alternative Name (s) : Spasmolysin, SP
Gene Names: TFF2,SML1
Research Areas: Cell Biology
Species: Homo sapiens (Human)
Source: E.Coli
Tag Info: Tag-Free
Expression Region: 24-129aa
Sequence Info: EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 × 105 IU/mg.
MW: 12.0 kDa
Purity: >97% as determined by SDS-PAGE and HPLC.
Endotoxin: Less than 1.0 EU/µg as determined by LAL method.
Relevance: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity) . {ECO:0000250}.
PubMed ID: 2303034; 9070946; 10950923; 15489334
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Function: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity) .
Involvement in disease:
Subcellular Location: Secreted
Protein Families:
Tissue Specificity: Stomach.
Paythway:
Form: Lyophilized powder
Buffer: Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 130mM NaCl
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q03403
Uniprot Entry Name: TFF2_HUMAN
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM