Recombinant Human Thyrotropin subunit beta (TSHB) | CSB-EP025130HU

Recombinant Human Thyrotropin subunit beta (TSHB) | CSB-EP025130HU | Cusabio

Alternative Name(s): Thyroid-stimulating hormone subunit beta ;TSH-B ;TSH-betaThyrotropin beta chainINN: Thyrotropin alfa

Gene Names: TSHB

Research Areas: Signal Transduction

Organism: Homo sapiens (Human)

AA Sequence: FCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSY

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 21-132aa

Sequence Info: Full Length of Mature Protein

MW: 28.9 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Indispensable for the control of thyroid structure and metabolism.

Reference: A novel thyroid stimulating hormone beta-subunit isoform in human pituitary, peripheral blood leukocytes, and thyroid.Schaefer J.S., Klein J.R.Gen. Comp. Endocrinol. 162:241-244(2009)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Indispensable for the control of thyroid structure and metabolism.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: Glycoprotein hormones subunit beta family

Tissue Specificity:

Paythway: Th17celldifferentiation

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P01222

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM