Recombinant Human Syntaxin-11 (STX11) | CSB-EP022889HU

Recombinant Human Syntaxin-11 (STX11) | CSB-EP022889HU | Cusabio

Alternative Name(s): FHL4; HLH4; HPLH4 ; Stx11; STX11_HUMAN; Syntaxin 11 ; Syntaxin-11

Gene Names: STX11

Research Areas: Tags & Cell Markers

Organism: Homo sapiens (Human)

AA Sequence: MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK

Source: E.coli

Tag Info: N-terminal GST-tagged

Expression Region: 1-287aa

Sequence Info: Full Length

MW: 60.2 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.

Reference: "Syntaxin 11: a member of the syntaxin family without a carboxyl terminal transmembrane domain." Tang B.L., Low D.Y.H., Hong W. Biochem. Biophys. Res. Commun. 245:627-632(1998)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.

Involvement in disease: Familial hemophagocytic lymphohistiocytosis 4 (FHL4)

Subcellular Location: Membrane, Peripheral membrane protein, Golgi apparatus, trans-Golgi network membrane, Peripheral membrane protein

Protein Families: Syntaxin family

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: O75558

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM