Recombinant Human Syntaxin-10 (STX10), partial | CSB-EP022888HU

Recombinant Human Syntaxin-10 (STX10), partial | CSB-EP022888HU | Cusabio

Alternative Name(s): STX10; SYN10; Syntaxin-10; Syn10

Gene Names: STX10

Research Areas: Signal Transduction

Organism: Homo sapiens (Human)

AA Sequence: SLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQ

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 2-228aa

Sequence Info: Cytoplasmic Domain

MW: 41.7 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

Reference: Syntaxin 10 a member of the syntaxin family localized to the trans-Golgi network.Tang B.L., Low D.Y.H., Tan A.E.H., Hong W.Biochem. Biophys. Res. Commun. 242:345-350(1998)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

Involvement in disease:

Subcellular Location: Golgi apparatus membrane, Single-pass type IV membrane protein

Protein Families: Syntaxin family

Tissue Specificity: Expressed at high levels in heart, skeletal muscle and pancreas.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: O60499

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM