Recombinant Human Superoxide dismutase [Cu-Zn] protein (SOD1) (Active) | CSB-AP000121HU

Recombinant Human Superoxide dismutase [Cu-Zn] protein (SOD1) (Active) | CSB-AP000121HU | Cusabio

Protein Description: Full Length of Mature Protein

Alternative Name (s) : EC 1.15.1.1, hSod1

Gene Names: SOD1

Research Areas: Cancer

Species: Homo sapiens (Human)

Source: E.Coli

Tag Info: N-terminal 6xHis-tagged

Expression Region: 2-154aa

Sequence Info: MGHHHHHHHH HHSSGHIEGR HMTYARAAAR QARALE+ATKA VCVLKGDGPV QGIINFEQKE SNGPVKVWGS IKGLTEGLHG FHVHEFGDNT AGCTSAGPHF NPLSRKHGGP KDEERHVGDL GNVTADKDGV ADVSIEDSVI SLSGDHCIIG RTLVVHEKAD DLGKGGNEES TKTGNAGSRL ACGVIGIAQ

Biological Activity: Fully biologically active when compared to standard. The potency per mg was determined by Pyrogallic Acid method and was found to be more than 1.0 × 104 IU/mg.

MW: 20 kDa

Purity: >95% as determined by SDS-PAGE and HPLC.

Endotoxin: Less than 1.0 EU/µg as determined by LAL method.

Relevance: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

PubMed ID: 6577438; 3160582; 3889846; 2853161; 14702039; 10830953; 15489334; 6770891; 7002610; 8528216; 8682505; 15326189; 18669648; 19608861; 20600836; 20068231; 21269460; 22496122; 22905912; 24140062; 23625804; 24275569; 1463506; 9541385; 9718300; 10329151; 12911296; 12963370; 12754496; 15056757; 16291742; 16406071; 17070542; 17888947; 17548825; 18378676; 8592323; 20727846; 8446170; 8351519; 8179602; 7980516; 8069312; 7951252; 7881433; 7836951; 7997024; 7870076; 7887412; 7795609; 7655468; 7655469; 7655471; 7700376; 7647793; 7501156; 7496169; 8938700; 8907321; 8990014; 9101297; 9455977; 10732812; 9131652; 10400992; 10430435; 11535232; 11369193; 12402272; 12145308; 14506936; 18552350; 18301754; 19741096; 21247266; 21220647

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Involvement in disease: Amyotrophic lateral sclerosis 1 (ALS1)

Subcellular Location: Cytoplasm, Mitochondrion, Nucleus

Protein Families: Cu-Zn superoxide dismutase family

Tissue Specificity:

Paythway:

Form: Lyophilized powder

Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P00441

Uniprot Entry Name: SODC_HUMAN

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM