Recombinant Human Ras-related protein Rab-2A (RAB2A) | CSB-EP019180HU

Recombinant Human Ras-related protein Rab-2A (RAB2A) | CSB-EP019180HU | Cusabio

Alternative Name(s): 9330148M11Rik; C80220; GTP binding protein; LHX; OTTMUSP00000004796; RAB2; RAB2 member RAS oncogene family; RAB2A; RAB2A; member RAS oncogene family; RAB2A_HUMAN; Ras related protein Rab 2A; RAS-associated protein RAB2; Ras-related protein Rab-2A; RP23-183L6.1; Small GTP binding protein RAB2A

Gene Names: RAB2A

Research Areas: Cancer

Organism: Homo sapiens (Human)

AA Sequence: AYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 2-212aa

Sequence Info: Full Length of Mature Protein

MW: 39.4 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Required for protein transport from the endoplasmic reticulum to the Golgi complex.

Reference: Nucleotide sequence of a new YPT1-related human cDNA which belongs to the ras gene superfamily.Tachibana K., Umezawa A., Kato S., Takano T.Nucleic Acids Res. 16:10368-10368(1988)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Required for protein transport from the endoplasmic reticulum to the Golgi complex.

Involvement in disease:

Subcellular Location: Endoplasmic reticulum-Golgi intermediate compartment membrane, Lipid-anchor, Melanosome, Endoplasmic reticulum membrane, Lipid-anchor, Golgi apparatus membrane, Lipid-anchor

Protein Families: Small GTPase superfamily, Rab family

Tissue Specificity:

Paythway: AMPKSignaling

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P61019

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM