Recombinant Human Mimecan (OGN) | CSB-EP016314HU

Recombinant Human Mimecan (OGN) | CSB-EP016314HU | Cusabio

Alternative Name(s): OsteoglycinOsteoinductive factor ;OIF

Gene Names: OGN

Research Areas: Signal Transduction

Organism: Homo sapiens (Human)

AA Sequence: PPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF

Source: E.coli

Tag Info: N-terminal 6xHis-tagged

Expression Region: 21-298aa

Sequence Info: Full Length of Mature Protein

MW: 35.7 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

Reference: Molecular cloning of a novel bone-forming compound osteoinductive factor.Madisen L., Neubauer M., Plowman G., Rosen D.M., Segarini P.R., Dasch J.R., Thompson A.Y., Ziman J., Bentz H., Purchio A.F.DNA Cell Biol. 9:303-309(1990)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

Involvement in disease:

Subcellular Location: Secreted, extracellular space, extracellular matrix

Protein Families: Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily

Tissue Specificity: Bone.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P20774

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM