Recombinant Human Homeobox protein Hox-B4 (HOXB4) | CSB-YP010664HU

Recombinant Human Homeobox protein Hox-B4 (HOXB4) | CSB-YP010664HU | Cusabio

Alternative Name(s): Homeobox protein Hox-2.6Homeobox protein Hox-2F

Gene Names: HOXB4

Research Areas: Transcription

Organism: Homo sapiens (Human)

AA Sequence: MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESSFQPEAGFGRRAACTVQRYAACRDPGPPPPPPPPPPPPPPPGLSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGAAGSAGGPPGRPNGGPRAL

Source: Yeast

Tag Info: N-terminal 6xHis-tagged

Expression Region: 1-251aa

Sequence Info: Full Length

MW: 29.6 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Sequence-specific transcription factor which is part of a developmental regulatory syst that provides cells with specific positional identities on the anterior-posterior axis.

Reference: Expression of HOX homeogenes in human neuroblastoma cell culture lines.Peverali F.A., D'Esposito M., Acampora D., Bunone G., Negri M., Faiella A., Stornaiuolo A., Pannese M., Migliaccio E., Simeone A., Valle G.D., Boncinelli E.Differentiation 45:61-69(1990)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Involvement in disease:

Subcellular Location: Nucleus

Protein Families: Antp homeobox family, Deformed subfamily

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P17483

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: OMIM