Recombinant Human FK506-binding protein-like (FKBPL) | CSB-EP883441HU

Recombinant Human FK506-binding protein-like (FKBPL) | CSB-EP883441HU | Cusabio

Alternative Name(s): WAF-1/CIP1 stabilizing protein 39

Gene Names: FKBPL

Research Areas: Cell Biology

Organism: Homo sapiens (Human)

AA Sequence: METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG

Source: E.coli

Tag Info: N-terminal GST-tagged

Expression Region: 1-349aa

Sequence Info: Full Length

MW: 65.2 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.

Reference: "A novel human stress response-related gene with a potential role in induced radioresistance." Robson T., Joiner M.C., Wilson G.D., McCullough W., Price M.E., Logan I., Jones H., McKeown S.R., Hirst D.G. Radiat. Res. 152:451-461(1999)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity: Ubiquitously expressed with higher levels in testis.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q9UIM3

HGNC Database Link: HGNC

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A