Recombinant Helicobacter pylori Cytotoxicity-associated immunodominant antigen (cagA), partial | CSB-EP301307HUS

Recombinant Helicobacter pylori Cytotoxicity-associated immunodominant antigen (cagA), partial | CSB-EP301307HUS | Cusabio

Alternative Name(s): 120KDA protein

Gene Names: cagA

Research Areas: Microbiology

Organism: Helicobacter pylori (Campylobacter pylori)

AA Sequence: KVNAKIDRLNQIASGLGVVGQAAGFPLKRHDKVDDLSKVGLSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTIDKLKDSTKHNPMNLWVESAKKVPASLSAKLDNYATNSHIRINSNIKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFSTKLNNAVKDTNSGFTQFLTNAFSTASYYCLARENAEHGIKNVNTKGGFQKS

Source: E.coli

Tag Info: N-terminal 6xHis-SUMO-tagged

Expression Region: 918-1147aa

Sequence Info: Partial

MW: 41.3 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: May be necessary for the transcription, folding, export, or function of the cytotoxin.

Reference: "Molecular characterization of the 128-KDA immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer." Covacci A., Censini S., Bugnoli M., Petracca R., Burroni D., Macchia G., Massone A., Papini E., Xiang Z., Figura N., Rappuoli R.Proc. Natl. Acad. Sci. U.S.A. 90:5791-5795(1993)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: May be necessary for the transcription, folding, export, or function of the cytotoxin.

Involvement in disease:

Subcellular Location:

Protein Families:

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P80200

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A