Recombinant Bovine Glycolipid transfer protein (GLTP) | CSB-YP009539BO

Recombinant Bovine Glycolipid transfer protein (GLTP) | CSB-YP009539BO | Cusabio

Alternative Name(s): GLTPGlycolipid transfer protein; GLTP

Gene Names: GLTP

Research Areas: Signal Transduction

Organism: Bos taurus (Bovine)

AA Sequence: ALLAEHLLRPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPTKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKVRLFLVNYTATIDVIYEMYTRMNAELNYKV

Source: Yeast

Tag Info: N-terminal 6xHis-tagged

Expression Region: 2-209aa

Sequence Info: Full Length of Mature Protein

MW: 25.8 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.

Reference: "Structural evidence for adaptive ligand binding of glycolipid transfer protein." Airenne T.T., Kidron H., Nymalm Y., Nylund M., West G., Mattjus P., Salminen T.A. J. Mol. Biol. 355:224-236(2006)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.

Involvement in disease:

Subcellular Location: Cytoplasm

Protein Families: GLTP family

Tissue Specificity: Detected in brain, kidney, spleen, lung, cerebellum, liver and heart.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P68265

HGNC Database Link: N/A

UniGene Database Link: UniGene

KEGG Database Link: KEGG

STRING Database Link: STRING

OMIM Database Link: N/A