Recombinant Anguilla japonica C-type natriuretic peptide (cnp) | CSB-YP323831BZH

Recombinant Anguilla japonica C-type natriuretic peptide (cnp) | CSB-YP323831BZH | Cusabio

Alternative Name(s): BNP-like peptide CNP-22

Gene Names: cnp

Research Areas: Others

Organism: Anguilla japonica (Japanese eel)

AA Sequence: GWNRGCFGLKLDRIGSLSGLGC

Source: Yeast

Tag Info: N-terminal 6xHis-tagged and C-terminal Myc-tagged

Expression Region: 110-131aa

Sequence Info: Full Length of Mature Protein

MW: 5.8 kDa

Purity: Greater than 90% as determined by SDS-PAGE.

Relevance: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. May be important for freshwater adaptation.

Reference: "Enhanced expression and release of C-type natriuretic peptide in freshwater eels." Takei Y., Inoue K., Ando K., Ihara T., Katafuchi T., Kashiwagi M., Hirose S. Am. J. Physiol. 280:R1727-1735(2001)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. May be important for freshwater adaptation.

Involvement in disease:

Subcellular Location: Secreted

Protein Families: Natriuretic peptide family

Tissue Specificity: Highly expressed in brain and liver, and moderately in gut, gills and heart. Expressed to a low level in atrium, ventricle and liver of fresh water eels.

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: P18145

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A