PRKAB1 Monoclonal Antibody | CSB-MA826344

PRKAB1 Monoclonal Antibody | CSB-MA826344 | Cusabio

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Product Type: Monoclonal Antibody

Target Name: PRKAB1

Aliases: 1300015D22Rik; 5 AMP activated protein kinase subunit beta 1; 5-AMP-activated protein kinase subunit beta-1; AAKB1_HUMAN; AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1; AMP-activated, noncatalytic, beta-1; AMPK; AMPK beta 1 chain;

Relevance: Non-catalytic subunit of AMP-activated protein kinase (AMPK) , an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton;probably by indirectly activating myosin.Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) .

Isotype: IgG

Conjugate: Non-conjugated

Clone Number:

Uniport ID: Q9Y478

Alternatives To SCBT:

Host Species: Mouse

Species Reactivity: Human, Mouse, Rat, Monkey

Immunogen: Purified recombinant human AMPK beta 1 protein fragments expressed in E.coli.

Immunogen Species: Human

Applications: ELISA, WB, IHC, ICC, IP

Tested Applications: ELISA, WB, IHC, ICC, IP;Recommended dilution:WB:1:500-1:5000, IHC:1:50-1:500, ICC:1:50-1:200, IP:1:200-1:2000

Purification Method: Affinity purified

Dilution Ratio1: WB:1:500-1:5000

Dilution Ratio2: IHC:1:50-1:500

Dilution Ratio3: ICC:1:50-1:200

Dilution Ratio4: IP:1:200-1:2000

Dilution Ratio5:

Buffer: Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Cardiovascular;Metabolism;Signal transduction