PPBP Antibody | CSB-PA09014A0Rb

PPBP Antibody | CSB-PA09014A0Rb | Cusabio

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Product Type: Polyclonal Antibody

Target Names: PPBP

Aliases: Platelet basic protein (PBP) (C-X-C motif chemokine 7) (Leukocyte-derived growth factor) (LDGF) (Macrophage-derived growth factor) (MDGF) (Small-inducible cytokine B7) [Cleaved into: Connective tissue-activating peptide III (CTAP-III) (LA-PF4) (Low-affinity platelet factor IV) ; TC-2; Connective tissue-activating peptide III (1-81) (CTAP-III (1-81) ) ; Beta-thromboglobulin (Beta-TG) ; Neutrophil-activating peptide 2 (74) (NAP-2 (74) ) ; Neutrophil-activating peptide 2 (73) (NAP-2 (73) ) ; Neutrophil-activating peptide 2 (NAP-2) ; TC-1; Neutrophil-activating peptide 2 (1-66) (NAP-2 (1-66) ) ; Neutrophil-activating peptide 2 (1-63) (NAP-2 (1-63) ) ], PPBP, CTAP3 CXCL7 SCYB7 TGB1 THBGB1

Background: LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2 (73), NAP-2 (74), NAP-2 (1-66), and most potent NAP-2 (1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III (1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P02775

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Platelet basic protein (59-125AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Cardiovascular;Immunology;Signal transduction