PLEKHO1 Antibody | CSB-PA105837

PLEKHO1 Antibody | CSB-PA105837 | Cusabio

PLEKHO1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: PLEKHO1

Aliases: pleckstrin homology domain containing, family O member 1

Background: Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by the PLEKHO1 gene.PLEKHO1 has been shown to interact with Casein kinase 2, alpha 1 and SMURF1.It plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP) . Appears to target ATM to the plasma membrane, and also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. The protein implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q53GL0

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Synthetic peptide of human PLEKHO1

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:25-1:100

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:1000-1:5000

Dilution Ratio2: IHC:1:25-1:100

Dilution Ratio3:

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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction