Cusabio Polyclonal Antibodies
Phospho-TP53 (Ser33) Antibody | CSB-PA029276
- SKU:
- CSB-PA029276
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
Phospho-TP53 (Ser33) Antibody | CSB-PA029276 | Cusabio
Phospho-TP53 (Ser33) Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: TP53
Aliases: P53, BCC7, LFS1, TRP53
Background:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
Lin T, et al. (2005) Nat Cell Biol; 7 (2) : 165-71.
Vega FM, et al. (2004) Mol Cell Biol; 24 (23) : 10366-80.
Li J, et al. (2004) J Biol Chem; 279 (40) : 41275-9.
Wang J, et al. (2004) J Biol Chem; 279 (38) : 39584-92.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P04637
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Peptide sequence around phosphorylation site of serine 33 (V-L-S (p) -P-L) derived from Human p53.
Immunogen Species: Human
Applications: ELISA, WB, IF
Tested Applications: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3: IF:1:100-1:200
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cell biology