Cusabio Polyclonal Antibodies
Phospho-SMAD3 (Ser204) Antibody | CSB-PA909608
- SKU:
- CSB-PA909608
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
Phospho-SMAD3 (Ser204) Antibody | CSB-PA909608 | Cusabio
Phospho-SMAD3 (Ser204) Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: SMAD3
Aliases: JV15-2; MAD-3; MADH3; Smad 3; Mothers against decapentaplegic homolog 3
Background:
Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24
Seong HA, Jung H, Ha H (2010) J Biol Chem 285, 30959-70
Zelivianski S, Cooley A, Kall R, Jeruss JS (2010) Mol Cancer Res 8, 1375-87
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P84022
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around phosphorylation site of serine204 (A-G-S (p) -P-N) derived from Human Smad3 .
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;WB:1:500-1:1000
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Epigenetics & Nuclear Signaling;Cancer;Metabolism;Signal transduction;Stem cells