Phospho-RPS6KB1 (Thr389/412) Antibody | CSB-PA073005

Phospho-RPS6KB1 (Thr389/412) Antibody | CSB-PA073005 | Cusabio

Phospho-RPS6KB1 (Thr389/412) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: RPS6KB1

Aliases: KS6B1; P70-S6K; RPS6KB1; Ribosomal protein S6 kinase; polypeptide 1

Background:

Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.

Hong S, et al. (2014) J Biol Chem
Puustinen P, et al. (2014) CJ Cell Biol 204, 713-27
Martineau Y, et al. (2014) Mol Cell Biol 34, 1046-53

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P23443

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence around phosphorylation site of threonine389/412 (G-F-T (p) -Y-V) derived from Human p70 S6 Kinase .

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics & Nuclear Signaling;Cell biology;Metabolism;Signal transduction