Phospho-RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6 (Ser221/227/S218/232) Antibody | CSB-PA182506

Phospho-RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6 (Ser221/227/S218/232) Antibody | CSB-PA182506 | Cusabio

Phospho-RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6 (Ser221/227/S218/232) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6

Aliases: KS6A1; KS6AA; MAPKAP-K1a; RSK1;

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.

Moller D.E., Am. J. Physiol. 266:C351-C359 (1994) .
Gregory S.G., Nature 441:315-321 (2006) .
The MGC Project Team, Genome Res. 14:2121-2127 (2004) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q15418/P51812/Q15349/Q9UK32

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Peptide sequence around phosphorylation site of Serine 221/227/218/232 (A-Y-S (p) -F-C) derived from Human RSK1/2/3/4.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Epigenetics & Nuclear Signaling;Signal transduction