Cusabio Polyclonal Antibodies
Phospho-RACGAP1 (Ser387) Antibody | CSB-PA443762
- SKU:
- CSB-PA443762
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
Phospho-RACGAP1 (Ser387) Antibody | CSB-PA443762 | Cusabio
Phospho-RACGAP1 (Ser387) Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: RACGAP1
Aliases: GTPase activating protein; GTPase activating protein ID-GAP; RAC GTPase- activating protein 1; RACGAP1; RAC GTPase-activating protein
Background:
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation.
Doki N, et al. (2009) Cancer Sci 100, 1675-9. Minoshima Y, et al. (2003) Dev Cell 4, 549-60.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q9H0H5
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around phosphorylation site of serine 387 (R-I-S (p) -G-C) derived from Human GTPase Activating Protein.
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;WB:1:500-1:1000
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Cell biology;Signal transduction