Phospho-PTPN11 (Y542) Antibody | CSB-RA019025A542phHU

Phospho-PTPN11 (Y542) Antibody | CSB-RA019025A542phHU | Cusabio

Phospho-PTPN11 (Y542) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Antibody Type: Recombinant Antibody

Target Names: PTPN11

Aliases: Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3, PTPN11, PTP2C, SHPTP2

Background: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).

Isotype: Rabbit IgG

Conjugate: Non-conjugated

Clonality: Monoclonal

Clone Number: 2,00E+02

Uniport ID: Q06124

Modified: Signal Transduction

species: Human

Species Reactivity: Human

Immunogen: A synthesized peptide derived from human Phospho-PTPN11 (Y542)

Tested Applications: ELISA, WB, IP; Recommended dilution: WB:1:500-1:5000, IP:1:200-1:1000

Purification Method: Affinity-chromatography

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.