Phospho-IRS1 (Ser312) Antibody | CSB-PA174165

Phospho-IRS1 (Ser312) Antibody | CSB-PA174165 | Cusabio

Phospho-IRS1 (Ser312) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: IRS1

Aliases: HIRS-1; IRS1; Insulin receptor substrate 1

Background: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit

Tzatsos A, et al. (2006) Mol Cell Biol; 26 (1) : 63-76
Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98 (8) : 4640-4645
Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97 (5) : 2355-2360
Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98 (8) : 4640-4645

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P35568

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence around phosphorylation site of serine 312 (A-T-S (p) -P-A) derived from Human IRS-1.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

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Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Tags & Cell Markers

Research Areas: Neuroscience;Cancer;Cardiovascular;Tags & Cell Markers;Metabolism;Signal transduction