Phospho-HCK (Tyr521) Antibody | CSB-PA033999

Phospho-HCK (Tyr521) Antibody | CSB-PA033999 | Cusabio

Phospho-HCK (Tyr521) Antibody is Available at Gentaur Genprice with the fastest delivery.

Online Order Payment is possible or send quotation to info@gentaur.com.

Product Type: Polyclonal Antibody

Target Names: HCK

Aliases: p59-HCK/p60-HCK; Hemopoietic cell kinas; Tyrosine-protein kinase HCK;

Background:

The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

Quintrell N., Mol. Cell. Biol. 7:2267-2275 (1987) [PubMed: 3496523].
Ziegler S.F., Mol. Cell. Biol. 7:2276-2285 (1987) [PubMed: 3453117].
Ota T., Nat. Genet. 36:40-45 (2004) [PubMed: 14702039].

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P08631

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence around phosphorylation site of tyrosine 521 (E-S-Q (p) -Y-Q) derived from Human HCK .

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Immunology;Signal transduction