Cusabio Polyclonal Antibodies
Phospho-FGFR1/FGFR2 (Tyr463/466) Antibody | CSB-PA443701
- SKU:
- CSB-PA443701
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
Phospho-FGFR1/FGFR2 (Tyr463/466) Antibody | CSB-PA443701 | Cusabio
Phospho-FGFR1/FGFR2 (Tyr463/466) Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: FGFR1/FGFR2
Aliases: BFGFR; CEK; FLG; CD331; FLT2
Background:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
Itoh N., Biochem. Biophys. Res. Commun. 169:680-685 (1990) .
Dionne C.A., EMBO J. 9:2685-2692 (1990) .
Johnson D.E., Mol. Cell. Biol. 10:4728-4736 (1990) .
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P11362/P21802
Host Species: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p) -E-L) derived from Human FGFR1/2.
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;WB:1:500-1:1000
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cardiovascular
Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cancer;Cardiovascular;Signal transduction