Phospho-ESR1 (Tyr537) Antibody | CSB-PA265011

Phospho-ESR1 (Tyr537) Antibody | CSB-PA265011 | Cusabio

Phospho-ESR1 (Tyr537) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ESR1

Aliases: ER; ESR; ESR1; ESTR; NR3A1

Background:

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Sehime Temel, Endocrinology, Oct 2002; 143: 3974.
Xin-Tian Zhang, AACR Meeting Abstracts, Apr 2005; 2005: 302.
Suwit J. Somponpun, Am J Physiol Regulatory Integrative Comp Physiol, Sep 2004; 287: R661 - R669.
Marcello Maggiolini, Cancer Res., Oct 1999;

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P03372

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Peptide sequence around phosphorylation site of tyrosine 537 (P-L-Y (p) -D-L) derived from Human Estrogen Receptor-α.

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3: IHC:1:50-1:100

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cancer;Signal transduction