Cusabio Polyclonal Antibodies
Phospho-EIF2AK2 (Thr446) Antibody | CSB-PA572393
- SKU:
- CSB-PA572393
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
Phospho-EIF2AK2 (Thr446) Antibody | CSB-PA572393 | Cusabio
Phospho-EIF2AK2 (Thr446) Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: EIF2AK2
Aliases: ADRB2; E2AK2; EIF2AK2; EIF2aK; PRKR
Background:
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
Abujiang Pataer, et, al. (2002) Cancer Res; 62: 2239.
K. D. Ryman, et, al. (2005) J. Virol; 79: 1487 - 1499.
Susana Guerra, et, al. (2006) J. Biol. Chem; 281: 18734 - 18745.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P19525
Host Species: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Peptide sequence around phosphorylation site of threonine 446 (K-R-T (p) -R-S) derived from Human PKR.
Immunogen Species: Human
Applications: ELISA, WB, IHC, IF
Tested Applications: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3: IHC:1:50-1:100
Dilution Ratio4: IF:1:100-1:200
Dilution Ratio5:
Dilution Ratio6:
Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Signal transduction