PDE6D Antibody | CSB-PA526126LA01HU

PDE6D Antibody | CSB-PA526126LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: PDE6D

Aliases: Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17), PDE6D, PDED

Background: Promotes the release of prenylated target proteins from cellular membranes (PubMed:9712853) . Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22002721, PubMed:23698361) . Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed:24166846) . Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity) . Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O43924

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit delta protein (1-150AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:2000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction