ORAI1 Antibody | CSB-PA846601LA01HU

ORAI1 Antibody | CSB-PA846601LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: ORAI1

Aliases: Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A), ORAI1, CRACM1 TMEM142A

Background: Ca (2+) release-activated Ca (2+) (CRAC) channel subunit which mediates Ca (2+) influx following depletion of intracellular Ca (2+) stores and channel activation by the Ca (2+) sensor, STIM1 (PubMed:16582901, PubMed:16645049, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:19249086, PubMed:23307288, PubMed:24351972, PubMed:24591628) . CRAC channels are the main pathway for Ca (2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q96D31

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Calcium release-activated calcium channel protein 1 protein (1-87AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology;Signal transduction