NPHS2 Antibody | CSB-PA579527

NPHS2 Antibody | CSB-PA579527 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: NPHS2

Aliases: nephrosis 2, idiopathic, steroid-resistant

Background: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN) . SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9NP85

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Synthetic peptide of human NPHS2

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:2000-1:5000

Dilution Ratio2: WB:1:200-1:1000

Dilution Ratio3: IHC:1:50-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cell biology;Tags & Cell Markers;Signal transduction