NOX4 Antibody, FITC conjugated | CSB-PA015961LC01HU

NOX4 Antibody, FITC conjugated | CSB-PA015961LC01HU | Cusabio

NOX4 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: NOX4

Aliases: NADPH oxidase 4 (EC 1.6.3.-) (Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) (Renal NAD (P) H-oxidase), NOX4, RENOX

Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q9NPH5

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human NADPH oxidase 4 protein (210-424AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Cardiovascular;Cell biology;Metabolism;Signal transduction