NFIL3 Antibody | CSB-PA621967ESR1HU

NFIL3 Antibody | CSB-PA621967ESR1HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: NFIL3

Aliases: Nuclear factor interleukin-3-regulated protein (E4 promoter-binding protein 4) (Interleukin-3 promoter transcriptional activator) (Interleukin-3-binding protein 1) (Transcriptional activator NF-IL3A), NFIL3, E4BP4 IL3BP1

Background: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity) . Represses transcriptional activity of PER1 (By similarity) . Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity) . Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity) . Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity) . Protects pro-B cells from programmed cell death (By similarity) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q16649

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Nuclear factor interleukin-3-regulated protein (133-462AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:1000-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Epigenetics & Nuclear Signaling;Immunology